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Distinct roles for CREB-binding protein and p300 in hematopoietic stem cell self-renewal

Hematopoietic stem cells (HSC) are tightly regulated through, as yet, undefined mechanisms that balance self-renewal and differentiation. We have identified a role for the transcriptional coactivators CREB-binding protein (CBP) and p300 in such HSC fate decisions. A full dose of CBP, but not p300, i...

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I publikationen:Proc Natl Acad Sci U S A
Huvudupphov: Rebel, Vivienne I., Kung, Andrew L., Tanner, Elizabeth A., Yang, Hong, Bronson, Roderick T., Livingston, David M.
Materialtyp: Artigo
Språk:Inglês
Utgiven: National Academy of Sciences 2002
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC137497/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12397173/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.232568499
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