Pre-steady-state DNA unwinding by bacteriophage T4 Dda helicase reveals a monomeric molecular motor

Helicases are molecular motor enzymes that unwind and translocate nucleic acids. One of the central questions regarding helicase activity is whether the process of coupling ATP hydrolysis to DNA unwinding requires an oligomeric form of the enzyme. We have applied a pre-steady-state kinetics approach...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Nanduri, Bindu, Byrd, Alicia K., Eoff, Robert L., Tackett, Alan J., Raney, Kevin D.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2002
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC137486/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12411580/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.232401899
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