Pre-steady-state DNA unwinding by bacteriophage T4 Dda helicase reveals a monomeric molecular motor

Helicases are molecular motor enzymes that unwind and translocate nucleic acids. One of the central questions regarding helicase activity is whether the process of coupling ATP hydrolysis to DNA unwinding requires an oligomeric form of the enzyme. We have applied a pre-steady-state kinetics approach...

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Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	Nanduri, Bindu, Byrd, Alicia K., Eoff, Robert L., Tackett, Alan J., Raney, Kevin D.
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 2002
Sujets:	Biological Sciences
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC137486/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12411580/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.232401899
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