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Antiproliferative effect in chronic myeloid leukaemia cells by antisense peptide nucleic acids

Peptide nucleic acid (PNA) is a synthetic DNA analogue that is resistant to nucleases and proteases and binds with exceptional affinity to RNA. Because of these properties PNA has the potential to become a powerful therapeutic agent to be used in vivo. Until now, however, the use of PNA in vivo has...

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Autori principali: Rapozzi, Valentina, Burm, Brigitte E. A., Cogoi, Susanna, van der Marel, Gijs A., van Boom, Jacques H., Quadrifoglio, Franco, Xodo, Luigi E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC137404/
https://ncbi.nlm.nih.gov/pubmed/12202756
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