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Molecular Targets Versus Models for New Antiepileptic Drug Discovery

Animal models have played a key role in the discovery and characterization of all marketed antiepileptic drugs (AED). The conventional wisdom is that the standard animal screening models are becoming obsolete because they fail to identify compounds that act in mechanistically new ways and as a resul...

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Hlavní autor: Rogawski, Michael A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1373807/
https://ncbi.nlm.nih.gov/pubmed/16377151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.eplepsyres.2005.09.012
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