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Molecular Targets Versus Models for New Antiepileptic Drug Discovery

Animal models have played a key role in the discovery and characterization of all marketed antiepileptic drugs (AED). The conventional wisdom is that the standard animal screening models are becoming obsolete because they fail to identify compounds that act in mechanistically new ways and as a resul...

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Detalhes bibliográficos
Autor principal: Rogawski, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1373807/
https://ncbi.nlm.nih.gov/pubmed/16377151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.eplepsyres.2005.09.012
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