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Actin and agonist MHC–peptide complex–dependent T cell receptor microclusters as scaffolds for signaling

T cell receptor (TCR) microclusters form within seconds of T cell contact with supported planar bilayers containing intercellular adhesion molecule-1 and agonist major histocompatibility complex (MHC)–peptide complexes, and elevation of cytoplasmic Ca(2+) is observed within seconds of the first dete...

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Autors principals: Campi, Gabriele, Varma, Rajat, Dustin, Michael L.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2005
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1373686/
https://ncbi.nlm.nih.gov/pubmed/16216891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20051182
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