Reduced hippocampal activation during episodic encoding in middle-aged individuals at genetic risk of Alzheimer's Disease: a cross-sectional study

BACKGROUND: The presence of the apolipoprotein E (APOE) ε4 allele is a major risk factor for the development of Alzheimer's disease (AD), and has been associated with metabolic brain changes several years before the onset of typical AD symptoms. Functional MRI (fMRI) is a brain imaging techniqu...

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Detalhes bibliográficos
Main Authors: Trivedi, Mehul A, Schmitz, Taylor W, Ries, Michele L, Torgerson, Britta M, Sager, Mark A, Hermann, Bruce P, Asthana, Sanjay, Johnson, Sterling C
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1373642/
https://ncbi.nlm.nih.gov/pubmed/16412236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1741-7015-4-1
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