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Exp5 exports eEF1A via tRNA from nuclei and synergizes with other transport pathways to confine translation to the cytoplasm

Importin β-type transport receptors mediate the vast majority of transport pathways between cell nucleus and cytoplasm. We identify here the translation elongation factor 1A (eEF1A) as the predominant nuclear export substrate of RanBP21/exportin 5 (Exp5). This cargo–exportin interaction is rather un...

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Main Authors: Bohnsack, Markus T., Regener, Kathrin, Schwappach, Blanche, Saffrich, Rainer, Paraskeva, Efrosyni, Hartmann, Enno, Görlich, Dirk
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2002
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC137205/
https://ncbi.nlm.nih.gov/pubmed/12426392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf613
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