Exp5 exports eEF1A via tRNA from nuclei and synergizes with other transport pathways to confine translation to the cytoplasm

Importin β-type transport receptors mediate the vast majority of transport pathways between cell nucleus and cytoplasm. We identify here the translation elongation factor 1A (eEF1A) as the predominant nuclear export substrate of RanBP21/exportin 5 (Exp5). This cargo–exportin interaction is rather un...

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Hlavní autoři: Bohnsack, Markus T., Regener, Kathrin, Schwappach, Blanche, Saffrich, Rainer, Paraskeva, Efrosyni, Hartmann, Enno, Görlich, Dirk
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2002
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC137205/
https://ncbi.nlm.nih.gov/pubmed/12426392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf613
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