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A secreted soluble form of ApoE receptor 2 acts as a dominant-negative receptor and inhibits Reelin signaling
Specialized neurons throughout the developing central nervous system secrete Reelin, which binds to ApoE receptor 2 (ApoER2) and very low density lipoprotein receptor (VLDLR), triggering a signal cascade that guides neurons to their correct position. Binding of Reelin to ApoER2 and VLDLR induces pho...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC137191/ https://ncbi.nlm.nih.gov/pubmed/12426372 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf599 |
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