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‘Super p53’ mice exhibit enhanced DNA damage response, are tumor resistant and age normally
The tumor suppressor p53 is critical in preventing cancer due to its ability to trigger proliferation arrest and cell death upon the occurrence of a variety of stresses, most notably, DNA damage and oncogenic stress. Here, we report the generation and characterization of mice carrying supernumerary...
Tallennettuna:
| Päätekijät: | , , , , , , , , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Oxford University Press
2002
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC137187/ https://ncbi.nlm.nih.gov/pubmed/12426394 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf595 |
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