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Functional interaction between DNA-PKcs and telomerase in telomere length maintenance
DNA-PKcs is the catalytic subunit of the DNA-dependent protein kinase (DNA-PK) complex that functions in the non-homologous end-joining of double-strand breaks, and it has been shown previously to have a role in telomere capping. In particular, DNA-PKcs deficiency leads to chromosome fusions involvi...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2002
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC137185/ https://ncbi.nlm.nih.gov/pubmed/12426399 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf593 |
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