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Functional interaction between DNA-PKcs and telomerase in telomere length maintenance

DNA-PKcs is the catalytic subunit of the DNA-dependent protein kinase (DNA-PK) complex that functions in the non-homologous end-joining of double-strand breaks, and it has been shown previously to have a role in telomere capping. In particular, DNA-PKcs deficiency leads to chromosome fusions involvi...

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Autores principales: Espejel, Silvia, Franco, Sonia, Sgura, Antonella, Gae, Darren, Bailey, Susan M., Taccioli, Guillermo E., Blasco, María A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2002
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC137185/
https://ncbi.nlm.nih.gov/pubmed/12426399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf593
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