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Nascent-peptide-mediated ribosome stalling at a stop codon induces mRNA cleavage resulting in nonstop mRNA that is recognized by tmRNA

Recent studies have established that tmRNA-mediated protein tagging occurs at stop codons depending on the C-terminal amino acid sequence of the nascent polypeptide immediately adjacent to those codons. We investigate here how the trans-translation at a stop codon occurs by using model crp genes enc...

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Autores principales: SUNOHARA, TAKAFUMI, JOJIMA, KAORU, YAMAMOTO, YASUFUMI, INADA, TOSHIFUMI, AIBA, HIROJI
Formato: Artigo
Lenguaje:Inglês
Publicado: Copyright 2004 by RNA Society 2004
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370933/
https://ncbi.nlm.nih.gov/pubmed/14970383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.5169404
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