Nascent-peptide-mediated ribosome stalling at a stop codon induces mRNA cleavage resulting in nonstop mRNA that is recognized by tmRNA

Ítems similars

• Protein tagging at rare codons is caused by tmRNA action at the 3′ end of nonstop mRNA generated in response to ribosome stalling
  per: LI, XIA, et al.
  Publicat: (2006)
• SsrA-mediated trans-translation plays a role in mRNA quality control by facilitating degradation of truncated mRNAs
  per: YAMAMOTO, YASUFUMI, et al.
  Publicat: (2003)
• tmRNA determinants required for facilitating nonstop mRNA decay
  per: Mehta, Preeti, et al.
  Publicat: (2006)
• The C-terminal amino acid sequence of nascent peptide is a major determinant of SsrA tagging at all three stop codons.
  per: Sunohara, Takafumi, et al.
  Publicat: (2002)
• Ribosome-associated Asc1/RACK1 is required for endonucleolytic cleavage induced by stalled ribosome at the 3′ end of nonstop mRNA
  per: Ikeuchi, Ken, et al.
  Publicat: (2016)