Large-Scale Evidence for the Effect of the COLIA1 Sp1 Polymorphism on Osteoporosis Outcomes: The GENOMOS Study

BACKGROUND: Osteoporosis and fracture risk are considered to be under genetic control. Extensive work is being performed to identify the exact genetic variants that determine this risk. Previous work has suggested that a G/T polymorphism affecting an Sp1 binding site in the COLIA1 gene is a genetic...

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Main Authors: Ralston, Stuart H, Uitterlinden, André G, Brandi, Maria Luisa, Balcells, Susana, Langdahl, Bente L, Lips, Paul, Lorenc, Roman, Obermayer-Pietsch, Barbara, Scollen, Serena, Bustamante, Mariona, Husted, Lise Bjerre, Carey, Alisoun H, Diez-Perez, Adolfo, Dunning, Alison M, Falchetti, Alberto, Karczmarewicz, Elzbieta, Kruk, Marcin, van Leeuwen, Johannes P. T. M., van Meurs, Joyce B. J., Mangion, Jon, McGuigan, Fiona E. A, Mellibovsky, Leonardo, del Monte, Francesca, Pols, Huibert A. P, Reeve, Jonathan, Reid, David M, Renner, Wilfried, Rivadeneira, Fernando, van Schoor, Natasja M., Sherlock, Rachael E, Ioannidis, John P. A
格式: Artigo
語言:Inglês
出版: Public Library of Science 2006
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370920/
https://ncbi.nlm.nih.gov/pubmed/16475872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.0030090
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