Ribosomes containing mutants of L4 ribosomal protein from Thermus thermophilus display multiple defects in ribosomal functions and sensitivity against erythromycin

Protein L4 from Thermus thermophilus (TthL4) was heterologously overproduced in Escherichia coli cells. To study the implication of the extended loop of TthL4 in the exit-tunnel and peptidyltransferase functions, the highly conserved E56 was replaced by D or Q, while the semiconserved G55 was change...

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Egile Nagusiak: TSAGKALIA, AIKATERINI, LEONTIADOU, FOTINI, XAPLANTERI, MARIA A., PAPADOPOULOS, GEORGIOS, KALPAXIS, DIMITRIOS L., CHOLI-PAPADOPOULOU, THEODORA
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Copyright 2005 by RNA Society 2005
Gaiak:
Report
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370849/
https://ncbi.nlm.nih.gov/pubmed/16244130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2126205
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