HotKnots: Heuristic prediction of RNA secondary structures including pseudoknots

We present HotKnots, a new heuristic algorithm for the prediction of RNA secondary structures including pseudoknots. Based on the simple idea of iteratively forming stable stems, our algorithm explores many alternative secondary structures, using a free energy minimization algorithm for pseudoknot f...

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Bibliografiske detaljer
Main Authors: REN, JIHONG, RASTEGARI, BAHARAK, CONDON, ANNE, HOOS, HOLGER H.
Format: Artigo
Sprog:Inglês
Udgivet: Copyright 2005 by RNA Society 2005
Fag:
Bioinformatics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370833/
https://ncbi.nlm.nih.gov/pubmed/16199760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.7284905
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