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Ribavirin is not a functional mimic of the 7-methyl guanosine mRNA cap

Ribavirin is a guanosine ribonucleoside analog that displays broad-spectrum anti-viral activity and is currently used for the treatment of some viral infections. Ribavirin has recently been proposed to also be a mimic of the 7-methyl guanosine cap found at the 5′ end of mRNAs. To obtain supporting f...

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Main Authors: YAN, YIFEI, SVITKIN, YURI, LEE, JOSEPH M., BISAILLON, MARTIN, PELLETIER, JERRY
格式: Artigo
語言:Inglês
出版: Copyright 2005 by RNA Society 2005
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370807/
https://ncbi.nlm.nih.gov/pubmed/16043507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2930805
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