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RNA secondary structure prediction by centroids in a Boltzmann weighted ensemble

Prediction of RNA secondary structure by free energy minimization has been the standard for over two decades. Here we describe a novel method that forsakes this paradigm for predictions based on Boltzmann-weighted structure ensemble. We introduce the notion of a centroid structure as a representativ...

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Detalhes bibliográficos
Main Authors: DING, YE, CHAN, CHI YU, LAWRENCE, CHARLES E.
Formato: Artigo
Idioma:Inglês
Publicado em: Copyright 2005 by RNA Society 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370799/
https://ncbi.nlm.nih.gov/pubmed/16043502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2500605
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