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Structural RNA has lower folding energy than random RNA of the same dinucleotide frequency

We present results of computer experiments that indicate that several RNAs for which the native state (minimum free energy secondary structure) is functionally important (type III hammerhead ribozymes, signal recognition particle RNAs, U2 small nucleolar spliceosomal RNAs, certain riboswitches, etc....

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Detalhes bibliográficos
Main Authors: CLOTE, PETER, FERRÉ, FABRIZIO, KRANAKIS, EVANGELOS, KRIZANC, DANNY
Formato: Artigo
Idioma:Inglês
Publicado em: Copyright 2005 by RNA Society 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370746/
https://ncbi.nlm.nih.gov/pubmed/15840812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.7220505
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