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No evidence that mRNAs have lower folding free energies than random sequences with the same dinucleotide distribution.

This work investigates whether mRNA has a lower estimated folding free energy than random sequences. The free energy estimates are calculated by the mfold program for prediction of RNA secondary structures. For a set of 46 mRNAs it is shown that the predicted free energy is not significantly differe...

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Detalhes bibliográficos
Main Authors: Workman, C, Krogh, A
Formato: Artigo
Idioma:Inglês
Publicado em: 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC148783/
https://ncbi.nlm.nih.gov/pubmed/10572183
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