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Interference probing of rRNA with snoRNPs: A novel approach for functional mapping of RNA in vivo

Synthesis of eukaryotic ribosomal RNAs (rRNAs) includes methylation of scores of nucleotides at the 2′-O-ribose position (Nm) by small nucleolar RNP complexes (snoRNPs). Sequence specificity is provided by the snoRNA component through base-pairing of a guide sequence with rRNA. Here, we report that...

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Autori principali: LIU, BEN, FOURNIER, MAURILLE J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Copyright 2004 by RNA Society 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370603/
https://ncbi.nlm.nih.gov/pubmed/15208448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.7190104
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