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Multiple functions for the invariant AGC triad of U6 snRNA

The invariant AGC triad of U6 snRNA plays an essential, unknown role in splicing. The triad has been implicated in base-pairing with residues in U2, U4, and U6. Through a genetic analysis in S. cerevisiae, we found that most AGC mutants are suppressed both by restoring pairing with U2, supporting th...

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Détails bibliographiques
Auteurs principaux: HILLIKER, ANGELA K., STALEY, JONATHAN P.
Format: Artigo
Langue:Inglês
Publié: Copyright 2004 by RNA Society 2004
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370584/
https://ncbi.nlm.nih.gov/pubmed/15146076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.7310704
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