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Multiple functions for the invariant AGC triad of U6 snRNA

The invariant AGC triad of U6 snRNA plays an essential, unknown role in splicing. The triad has been implicated in base-pairing with residues in U2, U4, and U6. Through a genetic analysis in S. cerevisiae, we found that most AGC mutants are suppressed both by restoring pairing with U2, supporting th...

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Detalhes bibliográficos
Main Authors: HILLIKER, ANGELA K., STALEY, JONATHAN P.
Formato: Artigo
Idioma:Inglês
Publicado em: Copyright 2004 by RNA Society 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370584/
https://ncbi.nlm.nih.gov/pubmed/15146076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.7310704
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