A single polypyrimidine tract binding protein (PTB) binding site mediates splicing inhibition at mouse IgM exons M1 and M2

Splicing of mouse immunoglobulin (IgM) exons M1 and M2 is directed by two juxtaposed regulatory elements, an enhancer and an inhibitor, located within the M2 exon. A primary function of the enhancer is to counteract the inhibitor, allowing splicing to occur. Here we show that the inhibitor contains...

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Autores principales: SHEN, HAIHONG, KAN, JULIE L.C., GHIGNA, CLAUDIA, BIAMONTI, GIUSEPPE, GREEN, MICHAEL R.
Formato: Artigo
Lenguaje:Inglês
Publicado: Copyright 2004 by RNA Society 2004
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370569/
https://ncbi.nlm.nih.gov/pubmed/15100434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.5229704
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