Two strategically placed base pairs in helix 8 of mammalian signal recognition particle RNA are crucial for the SPR19-dependent binding of protein SRP54

Signal recognition particle (SRP) guides secretory proteins to biological membranes in all organisms. Assembly of the large domain of mammalian SRP requires binding of SRP19 prior to the binding of protein SRP54 to SRP RNA. The crystal structure of the ternary complex reveals the parallel arrangemen...

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Bibliografiska uppgifter
Huvudupphovsmän: YIN, JIAMING, YANG, CHING-HUI, ZWIEB, CHRISTIAN
Materialtyp: Artigo
Språk:Inglês
Publicerad: Copyright 2004 by RNA Society 2004
Ämnen:
Report
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370547/
https://ncbi.nlm.nih.gov/pubmed/15037766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.5232404
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