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Two strategically placed base pairs in helix 8 of mammalian signal recognition particle RNA are crucial for the SPR19-dependent binding of protein SRP54
Signal recognition particle (SRP) guides secretory proteins to biological membranes in all organisms. Assembly of the large domain of mammalian SRP requires binding of SRP19 prior to the binding of protein SRP54 to SRP RNA. The crystal structure of the ternary complex reveals the parallel arrangemen...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
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Copyright 2004 by RNA Society
2004
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1370547/ https://ncbi.nlm.nih.gov/pubmed/15037766 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.5232404 |
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