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Nonspecific, concentration-dependent stimulation and repression of mammalian gene expression by small interfering RNAs (siRNAs)

RNA interference is an evolutionarily conserved process in which expression of a specific gene is post-transcriptionally inhibited by a small interfering RNA (siRNA), which recognizes a complementary mRNA and induces its degradation. Currently, RNA interference is being used extensively to inhibit e...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: PERSENGIEV, STEPHAN P., ZHU, XIAOCHUN, GREEN, MICHAEL R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Copyright 2004 by RNA Society 2004
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370513/
https://ncbi.nlm.nih.gov/pubmed/14681580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna5160904
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