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Combinatorial minimization and secondary structure determination of a nucleotide synthase ribozyme
We previously isolated from random sequences ribozymes able to form a glycosidic linkage between a ribose sugar and 4-thiouracil in a reaction that mimics protein-catalyzed nucleotide synthesis. Here we report on two serial in vitro selection experiments that defined the core motif of one of the nuc...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Copyright 2003 by RNA Society
2003
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1370485/ https://ncbi.nlm.nih.gov/pubmed/13130135 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.5500603 |
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