A common speed limit for RNA-cleaving ribozymes and deoxyribozymes

It is widely believed that the reason proteins dominate biological catalysis is because polypeptides have greater chemical complexity compared with nucleic acids, and thus should have greater enzymatic power. Consistent with this hypothesis is the fact that protein enzymes typically exhibit chemical...

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Main Authors: BREAKER, RONALD R., EMILSSON, GAIL MITCHELL, LAZAREV, DENIS, NAKAMURA, SHINGO, PUSKARZ, IZABELA J., ROTH, ADAM, SUDARSAN, NARASIMHAN
Format: Artigo
Language:Inglês
Published: Copyright 2003 by RNA Society 2003
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370461/
https://ncbi.nlm.nih.gov/pubmed/12869706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.5670703
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