Biochemical analysis and scanning force microscopy reveal productive and nonproductive ADAR2 binding to RNA substrates

Scanning force microscopy (SFM) can be used to image biomolecules at high resolution. Here we demonstrate that single-molecule analysis by SFM complements biochemical data on RNA protein binding and can provide information that cannot be obtained by the usual biochemical methods. We have used this m...

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Bibliographic Details
Main Authors: KLAUE, YVONNE, KÄLLMAN, ANNIKA M., BONIN, MICHAEL, NELLEN, WOLFGANG, ÖHMAN, MARIE
Format: Artigo
Language:Inglês
Published: Copyright 2003 by RNA Society 2003
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370450/
https://ncbi.nlm.nih.gov/pubmed/12810917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2167603
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