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Determination of preferential binding sites for anti-dsRNA antibodies on double-stranded RNA by scanning force microscopy.

The monoclonal anti-dsRNA antibody J2 binds double-stranded RNAs (dsRNA) in an apparently sequence-nonspecific way. The mAb only recognizes antigens with double-stranded regions of at least 40 bp and its affinity to poly(A) poly(U) and to dsRNAs with mixed base pair composition is about tenfold high...

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Bibliografische gegevens
Hoofdauteurs: Bonin, M, Oberstrass, J, Lukacs, N, Ewert, K, Oesterschulze, E, Kassing, R, Nellen, W
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2000
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1369937/
https://ncbi.nlm.nih.gov/pubmed/10786847
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