Lentivirus-delivered stable gene silencing by RNAi in primary cells

Genome-wide genetic approaches have proven useful for examining pathways of biological significance in model organisms such as Saccharomyces cerevisiae, Drosophila melanogastor, and Caenorhabditis elegans, but similar techniques have proven difficult to apply to mammalian systems. Although manipulat...

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Detalhes bibliográficos
Main Authors: STEWART, SHEILA A., DYKXHOORN, DEREK M., PALLISER, DEBORAH, MIZUNO, HANA, YU, EVAN Y., AN, DONG SUNG, SABATINI, DAVID M., CHEN, IRVIN S.Y., HAHN, WILLIAM C., SHARP, PHILLIP A., WEINBERG, ROBERT A., NOVINA, CARL D.
Formato: Artigo
Idioma:Inglês
Publicado em: Copyright 2003 by RNA Society 2003
Assuntos:
Method
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370415/
https://ncbi.nlm.nih.gov/pubmed/12649500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2192803
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