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Gene silencing in Caenorhabditis elegans by transitive RNA interference
When a cell is exposed to double-stranded RNA (dsRNA), mRNA from the homologous gene is selectively degraded by a process called RNA interference (RNAi). Here, we provide evidence that dsRNA is amplified in Caenorhabditis elegans to ensure a robust RNAi response. Our data suggest a model in which mR...
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| Principais autores: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Copyright 2003 by RNA Society
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1370367/ https://ncbi.nlm.nih.gov/pubmed/12554873 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2650903 |
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