An H/ACA guide RNA directs U2 pseudouridylation at two different sites in the branchpoint recognition region in Xenopus oocytes.

U2 is the most extensively modified of all spliceosomal snRNAs. We previously showed that at least some of the internally modified nucleotides in U2 snRNA are required for snRNP biogenesis and pre-mRNA splicing. Recent work from several laboratories suggests that nuclear guide RNAs facilitate U2 snR...

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Detaylı Bibliyografya
Asıl Yazarlar: Zhao, Xinliang, Li, Zhu-Hong, Terns, Rebecca M, Terns, Michael P, Yu, Yi-Tao
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2002
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370357/
https://ncbi.nlm.nih.gov/pubmed/12515384
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