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A conserved Lsm-interaction motif in Prp24 required for efficient U4/U6 di-snRNP formation.

The assembly of the U4 and U6 snRNPs into the U4/U6 di-snRNP is necessary for pre-mRNA splicing, and in Saccharomyces cerevisiae requires the splicing factor Prp24. We have identified a family of Prp24 homologs that includes the human protein SART3/p110nrb, which had been identified previously as a...

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Библиографические подробности
Главные авторы: Rader, Stephen D, Guthrie, Christine
Формат: Artigo
Язык:Inglês
Опубликовано: 2002
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370345/
https://ncbi.nlm.nih.gov/pubmed/12458792
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