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Yeast Pescadillo is required for multiple activities during 60S ribosomal subunit synthesis.

The Pescadillo protein was identified via a developmental defect and implicated in cell cycle progression. Here we report that human Pescadillo and its yeast homolog (Yph1p or Nop7p) are localized to the nucleolus. Depletion of Nop7p leads to nuclear accumulation of pre-60S particles, indicating a d...

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Main Authors: Oeffinger, Marlene, Leung, Anthony, Lamond, Angus, Tollervey, David, Lueng, Anthony
Formato: Artigo
Idioma:Inglês
Publicado: 2002
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370283/
https://ncbi.nlm.nih.gov/pubmed/12022229
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