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Nop53p is required for late 60S ribosome subunit maturation and nuclear export in yeast

We report that Ypl146cp/Nop53p is associated with pre-60S ribosomal complexes and localized to the nucleolus and nucleoplasm. In cells depleted of Nop53p synthesis of the rRNA components of the 60S ribosomal subunit is severely inhibited, with strikingly strong accumulation of the 7S pre-rRNA and a...

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Auteurs principaux: THOMSON, EMMA, TOLLERVEY, DAVID
Format: Artigo
Langue:Inglês
Publié: Copyright 2005 by RNA Society 2005
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370805/
https://ncbi.nlm.nih.gov/pubmed/16043506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2720205
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