Altered discrimination of start codons and initiator tRNAs by mutant initiation factor 3.

IF3 is essential for ensuring the fidelity of the initiation step of translation in bacterial cells. Mutations at residues R99 and R131 in the C-terminal domain of the factor have previously been shown to increase initiation from the non-canonical GUA codon. Here we show that these mutant forms of I...

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主要な著者: O'Connor, M, Gregory, S T, Rajbhandary, U L, Dahlberg, A E
フォーマット: Artigo
言語:Inglês
出版事項: 2001
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370149/
https://ncbi.nlm.nih.gov/pubmed/11453069
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