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Development of a tRNA-dependent in vitro translation system.

A method is described for depleting rabbit reticulocyte lysates and wheat germ extracts of endogenous tRNAs by affinity chromatography using a matrix generated by coupling ethanolamine to epoxy-activated Sepharose 6B. Greater than 90% depletion of tRNA is achieved with the result that translation be...

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Bibliographic Details
Main Authors: Jackson, R J, Napthine, S, Brierley, I
Format: Artigo
Language:Inglês
Published: 2001
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370128/
https://ncbi.nlm.nih.gov/pubmed/11350040
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