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Construction of regulatable picornavirus IRESes as a test of current models of the mechanism of internal translation initiation.

Picornavirus internal ribosome entry sites (IRESs) are approximately 450 nt. RNA elements that direct internal initiation of translation, such that when placed between the two cistrons of a dicistronic construct, they drive independent translation of the downstream cistron. Consequently they have be...

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Bibliographische Detailangaben
Hauptverfasser: Pöyry, T A, Hentze, M W, Jackson, R J
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2001
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370117/
https://ncbi.nlm.nih.gov/pubmed/11350029
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