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Purification of Drosophila snRNPs and characterization of two populations of functional U1 particles.

U1 snRNP is required at an early stage during assembly of the spliceosome, the dynamic ribonucleoprotein (RNP) complex that performs nuclear pre-mRNA splicing. Here, we report the purification of U1 snRNP particles from Drosophila nuclear extracts and the characterization of their biochemical proper...

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Autors principals: Labourier, E, Rio, D C
Format: Artigo
Idioma:Inglês
Publicat: 2001
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370101/
https://ncbi.nlm.nih.gov/pubmed/11333025
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