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Purification of Drosophila snRNPs and characterization of two populations of functional U1 particles.

U1 snRNP is required at an early stage during assembly of the spliceosome, the dynamic ribonucleoprotein (RNP) complex that performs nuclear pre-mRNA splicing. Here, we report the purification of U1 snRNP particles from Drosophila nuclear extracts and the characterization of their biochemical proper...

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Detalhes bibliográficos
Main Authors: Labourier, E, Rio, D C
Formato: Artigo
Idioma:Inglês
Publicado em: 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370101/
https://ncbi.nlm.nih.gov/pubmed/11333025
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