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Deletion of a conserved dinucleotide inhibits the second step of group II intron splicing.

Few point mutations have been described that specifically inhibit the second step of group II intron splicing. Furthermore, the effects of such mutations are typically not apparent unless the mutations are studied in the context of a substrate that harbors a very short 5' exon. Truncation of th...

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Bibliographic Details
Main Authors: Mikheeva, S, Murray, H L, Zhou, H, Turczyk, B M, Jarrell, K A
Format: Artigo
Language:Inglês
Published: 2000
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370021/
https://ncbi.nlm.nih.gov/pubmed/11105751
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