A potential RNA drug target in the hepatitis C virus internal ribosomal entry site.

Subdomain IlId from the hepatitis C virus (HCV) internal ribosome entry site (IRES) has been shown to be essential for cap-independent translation. We have conducted a structural study of a 27-nt fragment, identical in sequence to IlId, to explore the structural features of this subdomain. The propo...

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Hlavní autoři: Klinck, R, Westhof, E, Walker, S, Afshar, M, Collier, A, Aboul-Ela, F
Médium: Artigo
Jazyk:Inglês
Vydáno: 2000
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370013/
https://ncbi.nlm.nih.gov/pubmed/11073218
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