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The 3' substrate determinants for the catalytic efficiency of the Bacillus subtilis RNase P holoenzyme suggest autolytic processing of the RNase P RNA in vivo.

We investigated the catalytic efficiency and the specificity of the Bacillus subtilis RNase P holoenzyme reaction with substrates that contain a single strand, a hairpin loop, or a tRNA 3' to the cleavage site. At a saturating ribozyme concentration, RNase P can cleave a single-stranded RNA at...

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Main Authors: Loria, A, Pan, T
格式: Artigo
語言:Inglês
出版: 2000
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370012/
https://ncbi.nlm.nih.gov/pubmed/11073217
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