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Mtt1 is a Upf1-like helicase that interacts with the translation termination factors and whose overexpression can modulate termination efficiency.

Translation termination is the final step that completes the synthesis of a polypeptide. Premature translation termination by introduction of a nonsense mutation leads to the synthesis of a truncated protein. We report the identification and characterization of the product of the MTT1 gene, a helica...

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Autores principales: Czaplinski, K, Majlesi, N, Banerjee, T, Peltz, S W
Formato: Artigo
Lenguaje:Inglês
Publicado: 2000
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1369953/
https://ncbi.nlm.nih.gov/pubmed/10836794
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