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Evidence for an RNA-based catalytic mechanism in eukaryotic nuclear ribonuclease P.

Ribonuclease P is the enzyme responsible for removing the 5'-leader segment of precursor transfer RNAs in all organisms. All eukaryotic nuclear RNase Ps are ribonucleoproteins in which multiple protein components and a single RNA species are required for activity in vitro as well as in vivo. It...

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Detalhes bibliográficos
Main Authors: Thomas, B C, Chamberlain, J, Engelke, D R, Gegenheimer, P
Formato: Artigo
Idioma:Inglês
Publicado em: 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1369936/
https://ncbi.nlm.nih.gov/pubmed/10786846
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