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A selection system for functional internal ribosome entry site (IRES) elements: analysis of the requirement for a conserved GNRA tetraloop in the encephalomyocarditis virus IRES.

Picornavirus internal ribosome entry site (IRES) elements direct cap-independent internal initiation of protein synthesis within mammalian cells. These RNA elements (about 450 nt) contain extensive secondary structure including a hairpin loop with a conserved GNRA motif. Such loops are important in...

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Detaylı Bibliyografya
Asıl Yazarlar: Robertson, M E, Seamons, R A, Belsham, G J
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1999
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1369840/
https://ncbi.nlm.nih.gov/pubmed/10496218
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